GPBAreceptoragonist.UpregulatesGLP-1secretionfromintestinalcultures.IncreasesMQAE-fluorescencesuggestingadecreaseinintracellularchlorideconcentrationingallbladderepithelialcells.
GPBAR-AisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 484.37 |
| Formula | C23H15F7N2O2 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 877052-79-4 |
| PubChemID | 11656002 |
| InChIKey | ZIXNJVGTAXRKAP-UHFFFAOYSA-N |
| Smiles | O=C(CO3)N(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)CC1=C3N=CC=C1C2=C(F)C=CC=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 48.44 | 100 | |
| ethanol | 9.69 | 20 |
Thefollowingdataisbasedontheproductmolecularweight484.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.06mL | 10.32mL | 20.65mL |
| 5mM | 0.41mL | 2.06mL | 4.13mL |
| 10mM | 0.21mL | 1.03mL | 2.06mL |
| 50mM | 0.04mL | 0.21mL | 0.41mL |



