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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GLPG 0974/5621/10/10 mg
产品编号:5621/10
市  场 价:¥4580.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$229.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GLPG 0974/5621/10/10 mg
商品介绍
Description:PotentFFA2antagoNIST
ChemicalName:4-[[[(2R)-1-(Benzo[b]thien-3-ylcarbonyl)-2-methyl-2-azetidinyl]carbonyl][(3-chlorophenyl)methyl]amino]butanoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentFFA2antagonist(IC50=9nM).ExhibitsselectivityforFFA2overFFA3.Inhibitsacetate-inducedhumanneutrophilmigrationinplasmaorbuffer.AlsoinhibitsFFA2-inducedexpressionofCD11bactivation-specificepitope(AE)inhumanwholeblood.Orallybioavailable.

TechnicalData

M.Wt485
FormulaC25H25ClN2O4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1391076-61-1
PubChemID57520598
InChIKeyMPMKMQHJHDHPBE-RUZDIDTESA-N
SmilesO=C(N1[C@](C(N(CC2=CC(Cl)=CC=C2)CCCC(O)=O)=O)(C)CC1)C3=CSC4=C3C=CC=C4

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.NaOH9.720mMwithgentlewarming
DMSO48.5100
ethanol48.5100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight485.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.06mL10.31mL20.62mL
5mM0.41mL2.06mL4.12mL
10mM0.21mL1.03mL2.06mL
50mM0.04mL0.21mL0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet