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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/G10/5944/10/10 mg
产品编号:5944/10
市  场 价:¥2500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$125.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/G10/5944/10/10 mg
商品介绍
Description:ActivatorofSTING-dependentsignaling
ChemicalName:4-[(2-Chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ActivatorofSTING-dependentsignaling;exhibitsnodirectbindingaffinityforSTING.StimulatesIRF-3-inducedtranscriptionandinducesIFNαandIFNγgeneexpressioninhumanfibroblasts.ExhibitsnoeffectonNF-κBsignaling.Blocksviralreplicationinvitro.

TechnicalData

M.Wt430.88
FormulaC21H16ClFN2O3S
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber702662-50-8
PubChemID5077622
InChIKeyNAGKYJATVFXZKN-UHFFFAOYSA-N
SmilesFC1=CC=CC(Cl)=C1CN2C(CSC3=CC=C(C(NCC4=CC=CO4)=O)C=C23)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.09100
ethanol2.155mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight430.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.32mL11.6mL23.21mL
5mM0.46mL2.32mL4.64mL
10mM0.23mL1.16mL2.32mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet