SubstanceP-relatedpeptidethatinhibitsbindingofGproteinstotheirreceptors.CompetitivelyandreversIBLyinhibitsM2muscarinicreceptoractivationofGiorGoandinhibitsGsactivationbyβ-adrenoceptors.
| M.Wt | 1093.27 |
| Formula | C57H64N12O9S |
| Sequence | XQWFWWM (Modifications:X=Glp,Trp-3=Trp-5=Trp-6=D-Trp,Met-7=C-terminalamide) |
| Storage | Desiccateat-20°C |
| CASNumber | 143675-79-0 |
| PubChemID | 71308571 |
| InChIKey | WSYRBHQWMXTCHQ-SFIKJRKMSA-N |
| Smiles | [H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solubility | Solubleto2mg/mlinDMSO |
Thefollowingdataisbasedontheproductmolecularweight1093.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.91mL | 4.57mL | 9.15mL |
| 5mM | 0.18mL | 0.91mL | 1.83mL |
| 10mM | 0.09mL | 0.46mL | 0.91mL |
| 50mM | 0.02mL | 0.09mL | 0.18mL |



