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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/G-15/3678/10/10 mg
产品编号:3678/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/G-15/3678/10/10 mg
商品介绍
Description:HighaffinityandselectiveGPERantagoNIST
ChemicalName:(3aS*,4R*,9bR*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta[c]quinoline
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityandselectiveGPERreceptorantagonist(Ki=20nM)thatdisplaysnoaffinityforERαandERβatconcentrationsupto10μM.Inhibitsagonist-inducedcalciummobilizationinvitro(EC50of~185nM)andantagonizestheantidepressiveandrenoprotectiveeffectsofestrogeninvivo.

TechnicalData

M.Wt370.24
FormulaC19H16BrNO2
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber1161002-05-6
PubChemID90488870
InChIKeyLBBDCJLRQXMUAE-FWHYVADDSA-N
SmilesBrC1=CC4=C(OCO4)C=[C@@]1[C@@H]2NC(C=CC=C5)=C5[C@@]3([H])[C@@]([H])2CC=C3.BrC6=CC9=C(OCO9)C=[C@@]6[C@H]7NC(C=CC=C%10)=C%10[C@]8([H])[C@]([H])7CC=C8

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO18.5150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight370.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.7mL13.5mL27.01mL
5mM0.54mL2.7mL5.4mL
10mM0.27mL1.35mL2.7mL
50mM0.05mL0.27mL0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet