LoopdiureticthatinhibitstheNa+/2Cl-/K+(NKCC)symporter.Alsoactsasanon-competitiveantagoNISTatGABAAreceptorswith~100-foldgreaterselectivityforα6-containingreceptorsthanα1-containingreceptors.
FurosemideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 330.74 |
| Formula | C12H11ClN2O5S |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 54-31-9 |
| PubChemID | 3440 |
| InChIKey | ZZUFCTLCJUWOSV-UHFFFAOYSA-N |
| Smiles | ClC1=CC(NCC2=CC=CO2)=C(C(O)=O)C=C1S(=O)(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.07 | 100 |
Thefollowingdataisbasedontheproductmolecularweight330.74.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.02mL | 15.12mL | 30.24mL |
| 5mM | 0.6mL | 3.02mL | 6.05mL |
| 10mM | 0.3mL | 1.51mL | 3.02mL |
| 50mM | 0.06mL | 0.3mL | 0.6mL |



