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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Fumitremorgin C/2876/250U/250 ug
产品编号:2876/250U
市  场 价:¥4100.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$205.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Fumitremorgin C/2876/250U/250 ug
商品介绍
Description:InhibitorofBCRP-mediatedmultidrugresistance
ChemicalName:(5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Chemosensitizingagent;selectivelyreversesBCRP-mediatedmultidrugresistancetomitoxantrone(Cat.No.4250),doxorubicin(Cat.No.2252)andtopotecan(Cat.No.4562)intransfectedMCF-7cells.DoesnotreverseresistanceinP-gp-orMRP-positivecells.Analog(Ko143,Cat.No.3241)alsoavailable.

TechnicalData

M.Wt379.45
FormulaC22H25N3O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber118974-02-0
PubChemID403923
InChIKeyDBEYVIGIPJSTOR-FHWLQOOXSA-N
SmilesO=[C@@]3N5[C@@H](CCC5)C(N([C@H]3C4)[C@@H](/C=C(C)/C)C2=C4C1=CC=C(OC)C=C1N2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO3.7910

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight379.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.64mL13.18mL26.35mL
5mM0.53mL2.64mL5.27mL
10mM0.26mL1.32mL2.64mL
50mM0.05mL0.26mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet