Cell-permeableactivatorofadenylylcyclase.Hypotensiveandvasodilatoryagent.Inducesneuronaldifferentiationinstemcellsandinseveralneuroblastoma.Usedtoreprogrammouseembryonicfibroblaststoinducedpluripotentstemcellsincombinationwiththreeothersmallmolecules(Cat.Nos.3742,4423and4703).AlsoavailableaspartofthePKATocriset™.
ForskolinisalsoofferedaspartoftheTocriscreenPlus,TocriscreenEpigeneticsToolboxandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 410.51 |
Formula | C22H34O7 |
Storage | Desiccateat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 66575-29-9 |
PubChemID | 47936 |
InChIKey | OHCQJHSOBUTRHG-KGGHGJDLSA-N |
Smiles | C=C[C@](C3)(C)O[C@]2(C)[C@@H](OC(C)=O)[C@@H](O)[C@@]1([H])C(C)(C)CC[C@H](O)[C@@](C)1[C@](O)2C3=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 10.26 | 25 | |
ethanol | 4.11 | 10 |
Thefollowingdataisbasedontheproductmolecularweight410.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.44mL | 12.18mL | 24.36mL |
5mM | 0.49mL | 2.44mL | 4.87mL |
10mM | 0.24mL | 1.22mL | 2.44mL |
50mM | 0.05mL | 0.24mL | 0.49mL |