RXRagonist(Ki=12nM;EC50=43nMatRXRαreceptors).DisplayssimilarRARagonistactivitytobexarotene;exhibitsanapparentRXRbindingaffinity75%greaterthanbexarotene.
ManufacturedandsoldunderlicensefromArizonaStateUniversity-PatentPending
| M.Wt | 366.47 |
| Formula | C24H27FO2 |
| Storage | Storeat+4°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 1190848-23-7 |
| PubChemID | 25195496 |
| InChIKey | LWKAWHRSPCHMPJ-UHFFFAOYSA-N |
| Smiles | CC(C(C(C3=CC=C(C(O)=O)C(F)=C3)=C)=C2)=CC1=C2C(C)(C)CCC(C)1C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 36.65 | 100 | |
| ethanol | 9.16 | 25 |
Thefollowingdataisbasedontheproductmolecularweight366.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.73mL | 13.64mL | 27.29mL |
| 5mM | 0.55mL | 2.73mL | 5.46mL |
| 10mM | 0.27mL | 1.36mL | 2.73mL |
| 50mM | 0.05mL | 0.27mL | 0.55mL |



