RXRagonist(Ki=12nM;EC50=43nMatRXRαreceptors).DisplayssimilarRARagonistactivitytobexarotene;exhibitsanapparentRXRbindingaffinity75%greaterthanbexarotene.
ManufacturedandsoldunderlicensefromArizonaStateUniversity-PatentPending
M.Wt | 366.47 |
Formula | C24H27FO2 |
Storage | Storeat+4°C |
Purity | ≥97%(HPLC) |
CASNumber | 1190848-23-7 |
PubChemID | 25195496 |
InChIKey | LWKAWHRSPCHMPJ-UHFFFAOYSA-N |
Smiles | CC(C(C(C3=CC=C(C(O)=O)C(F)=C3)=C)=C2)=CC1=C2C(C)(C)CCC(C)1C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 36.65 | 100 | |
ethanol | 9.16 | 25 |
Thefollowingdataisbasedontheproductmolecularweight366.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.73mL | 13.64mL | 27.29mL |
5mM | 0.55mL | 2.73mL | 5.46mL |
10mM | 0.27mL | 1.36mL | 2.73mL |
50mM | 0.05mL | 0.27mL | 0.55mL |