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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Fexaramine/2563/50/50 mg
产品编号:2563/50
市  场 价:¥16500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$825.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Fexaramine/2563/50/50 mg
商品介绍
Description:Potent,selectivefarnesoidXreceptor(FXR)agoNIST
ChemicalName:3-[3-[(Cyclohexylcarbonyl)-[[4'-(dimethylamino)-[1,1'-biphenyl]-4-yl]methyl]amino]phenyl]-2-propenoicacidmethylester
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectivefarnesoidXreceptoragonist(EC50=25nM).DisplaysnoactivityathRXRα,hPPARα,hPPARγ,hPPARδ,mPXR,hPXR,hLXRα,hTRβ,hRARβ,mCAR,mERRγandhVDRreceptors.

CompoundLibraries

FexaramineisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt496.64
FormulaC32H36N2O3
StorageDesiccateat+4°C
Purity≥97%(HPLC)
CASNumber574013-66-4
PubChemID5326713
InChIKeyVLQTUNDJHLEFEQ-KGENOOAVSA-N
SmilesO=C(C3CCCCC3)N(CC2=CC=C(C4=CC=C(N(C)C)C=C4)C=C2)C1=CC(/C=C/C(OC)=O)=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO49.66100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight496.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.01mL10.07mL20.14mL
5mM0.4mL2.01mL4.03mL
10mM0.2mL1.01mL2.01mL
50mM0.04mL0.2mL0.4mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet