Potent,selectivefarnesoidXreceptoragonist(EC50=25nM).DisplaysnoactivityathRXRα,hPPARα,hPPARγ,hPPARδ,mPXR,hPXR,hLXRα,hTRβ,hRARβ,mCAR,mERRγandhVDRreceptors.
FexaramineisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 496.64 |
Formula | C32H36N2O3 |
Storage | Desiccateat+4°C |
Purity | ≥97%(HPLC) |
CASNumber | 574013-66-4 |
PubChemID | 5326713 |
InChIKey | VLQTUNDJHLEFEQ-KGENOOAVSA-N |
Smiles | O=C(C3CCCCC3)N(CC2=CC=C(C4=CC=C(N(C)C)C=C4)C=C2)C1=CC(/C=C/C(OC)=O)=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 49.66 | 100 |
Thefollowingdataisbasedontheproductmolecularweight496.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.01mL | 10.07mL | 20.14mL |
5mM | 0.4mL | 2.01mL | 4.03mL |
10mM | 0.2mL | 1.01mL | 2.01mL |
50mM | 0.04mL | 0.2mL | 0.4mL |