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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/FLI 06/5172/10/10 mg
产品编号:5172/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/FLI 06/5172/10/10 mg
商品介绍
Description:InhibitorofNotchsignaling
ChemicalName:Cyclohexyl1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofNotchsignaling(EC50=2.3μM).DisruptsNotchtraffickingandprocessing.Reducesamyloidβsecretion.ChangesthematurationandabolishesshreddingofAPP.InhibitsERexportingandconvertstubularERtosheets.

CompoundLibraries

FLI06isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt438.52
FormulaC25H30N2O5
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber313967-18-9
PubChemID3103157
InChIKeySWWVFYHSSOWZMF-UHFFFAOYSA-N
SmilesO=C(OC3CCCCC3)C1=C(C)NC(CC(C)(C)CC4=O)=C4C1C2=CC=C([N+]([O-])=O)C=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.85100
ethanol8.7720

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight438.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.28mL11.4mL22.8mL
5mM0.46mL2.28mL4.56mL
10mM0.23mL1.14mL2.28mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet