ReversIBLeinhibitorofvesiculartraffickingbetweenendoplasmicreticulumandGolgiapparatus.ModifiesGolgiADP-ribosylationfactor(ARF)1GTPaseactivityandinhibitsexocytosis(IC50~20mM).Hassimilar,butnotidentical,actiontobrefeldinA(Cat.No.1231).
Exo1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 273.26 |
Formula | C15H12FNO3 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 461681-88-9 |
PubChemID | 310557 |
InChIKey | KIAPWMKFHIKQOZ-UHFFFAOYSA-N |
Smiles | COC(=O)C1=CC=CC=C1NC(=O)C1=CC=C(F)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 27.33 | 100 | |
ethanol | 6.83 | 25mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight273.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.66mL | 18.3mL | 36.6mL |
5mM | 0.73mL | 3.66mL | 7.32mL |
10mM | 0.37mL | 1.83mL | 3.66mL |
50mM | 0.07mL | 0.37mL | 0.73mL |