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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Exemestane/3759/10/10 mg
产品编号:3759/10
市  场 价:¥3180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$159.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Exemestane/3759/10/10 mg
商品介绍
Description:Steroidalaromatase(CYP19)inhibitor
AlternativeNames:FCE24304,EXE
ChemicalName:6-Methyleneandrosta-1,4-diene-3,17-dione
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

IrreversIBLesteroidalaromataseinhibitor(IC50=20nM).DestABIlizesaromataseandlowersestrogenlevels;orallyactive.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

CompoundLibraries

ExemestaneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt296.4
FormulaC20H24O2
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber107868-30-4
PubChemID60198
InChIKeyBFYIZQONLCFLEV-DAELLWKTSA-N
SmilesC[C@@]12C(C(C[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CCC4=O)=C)=CC(C=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO29.64100
ethanol22.2375

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight296.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.37mL16.87mL33.74mL
5mM0.67mL3.37mL6.75mL
10mM0.34mL1.69mL3.37mL
50mM0.07mL0.34mL0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet