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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Eplerenone/2397/10/10 mg
产品编号:2397/10
市  场 价:¥3100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$155.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Eplerenone/2397/10/10 mg
商品介绍
Description:SelectivemineralocorticoidreceptorantagoNIST
AlternativeNames:Inspra,Epoxymexrenone
ChemicalName:(7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylicacidγ-lactonemethylester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivemineralocorticoid(aldosterone)receptorantagonist(IC50=360nM).Displays>27-foldselectivityoverandrogen,progesteroneandestrogenreceptors(IC50>10μM).Orallyactiveantihypertensiveinvivo.

TechnicalData

M.Wt414.5
FormulaC24H30O6
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber107724-20-9
PubChemID443872
InChIKeyJUKPWJGBANNWMW-VWBFHTRKSA-N
SmilesO=C1CC[C@@]2(C)C(C[C@@H]([C@](OC)=O)[C@]3([H])[C@@](O6)2[C@H]6C[C@@]4(C)[C@]([H])3CC[C@@]54OC(CC5)=O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.1410

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight414.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.41mL12.06mL24.13mL
5mM0.48mL2.41mL4.83mL
10mM0.24mL1.21mL2.41mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet