Endogenousomega-3fattyacid.ActsasaselectiveretinoidXreceptor(RXR)agonistthatdisplaysnoactivityatRAR,thyroidhormonereceptororthevitaminDreceptor(VDR).ActivatesallthreeRXRisoforms.AlsoshowntoinhibitAβ1-42fibrillationandtoxicityinvitro.
| M.Wt | 328.49 |
| Formula | C22H32O2 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 6217-54-5 |
| PubChemID | 445580 |
| InChIKey | MBMBGCFOFBJSGT-KUBAVDMBSA-N |
| Smiles | CCC=C/CC=C/CC=C/C/C=CC/C=CC/C=CCCC(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 32.85 | 100 | |
| ethanol | 32.85 | 100 |
Thefollowingdataisbasedontheproductmolecularweight328.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.04mL | 15.22mL | 30.44mL |
| 5mM | 0.61mL | 3.04mL | 6.09mL |
| 10mM | 0.3mL | 1.52mL | 3.04mL |
| 50mM | 0.06mL | 0.3mL | 0.61mL |



