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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Dexrazoxane hydrochloride/3857/50/50 mg
产品编号:3857/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Dexrazoxane hydrochloride/3857/50/50 mg
商品介绍
Description:TopoisomeraseIIinhibitor
AlternativeNames:ICRF-187
ChemicalName:4-[(2S)-2-(3,5-Dioxopiperazin-1-yl)propyl]piperazine-2,6-dionehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

TopoisomeraseIIinhibitorandintracellularionchelator.BridgesandstABIlizesaninterfacebetweentwoATPasepromoterstoinhibittopoisomeraseIIactivity.Cardioprotectivewhenco-admiNISTeredwithdoxorubicin;decreasesformationofreactiveoxygenspecies(ROS)andactivatesthePI3K/Aktsurvivalpathway.

TechnicalData

M.Wt304.73
FormulaC11H16N4O4.HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1263283-43-7
PubChemID6918223
InChIKeyBIFMNMPSIYHKDN-FJXQXJEOSA-N
SmilesC[C@@H](CN2CC(NC(C2)=O)=O)N(CC(N1)=O)CC1=O.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.47100
water30.47100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight304.73.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.28mL16.41mL32.82mL
5mM0.66mL3.28mL6.56mL
10mM0.33mL1.64mL3.28mL
50mM0.07mL0.33mL0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet