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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Deguelin/1770/10/10 mg
产品编号:1770/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Deguelin/1770/10/10 mg
商品介绍
Description:Anticancerandantiviralagent;chemopreventiveandpro-apoptotic
ChemicalName:(7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Anticancerandantiviralagent;chemopreventiveandpro-apoptotic.Inhibitsphorbolester-inducedornithinedecarboxylaseandNADH:ubiquinoneoxidoreductaseactivities(IC50valuesare11and6.9nMrespectively).InhibitsPI3-kinaseandreducespAktlevelsinpre-malignantandmalignanthumanbronchialepithelialcells.Activeinvivo.

TechnicalData

M.Wt394.42
FormulaC23H22O6
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber522-17-8
PubChemID107935
InChIKeyORDAZKGHSNRHTD-UXHICEINSA-N
SmilesO=C(C(C=CC5=C4C=CC(C)(C)O5)=C4O3)[C@@]([C@@]3([H])CO2)([H])C1=C2C=C(OC)C(OC)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.44100
ethanol19.7250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight394.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.54mL12.68mL25.35mL
5mM0.51mL2.54mL5.07mL
10mM0.25mL1.27mL2.54mL
50mM0.05mL0.25mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet