请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/DSR 6434/4809/50/50 mg
产品编号:4809/50
市  场 价:¥16100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$805.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/DSR 6434/4809/50/50 mg
商品介绍
Description:PotentTLR7agoNIST
ChemicalName:6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentTLR7agonist(EC50=7.2nM).Activatesseveralimmuneeffectorcellsinvitro.SuppressesmetastasisinvivoandenhancesefficacyofrADIationtherapyinamodelofcolorectalcarcinoma.

CompoundLibraries

DSR6434isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt400.48
FormulaC19H28N8O2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1059070-10-8
PubChemID25071151
InChIKeySSZHESNDOMBSRV-UHFFFAOYSA-N
SmilesO=C2N(CC3=CC=C(OCCN(C)C)N=C3)C1=NC(NCCCC)=NC(N)=C1N2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl20.0250
DMSO40.05100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight400.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.5mL12.49mL24.97mL
5mM0.5mL2.5mL4.99mL
10mM0.25mL1.25mL2.5mL
50mM0.05mL0.25mL0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet