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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/DMXAA/5601/50/50 mg
产品编号:5601/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/DMXAA/5601/50/50 mg
商品介绍
Description:mSTINGagoNIST;inducesantitumorimmunologicalresponses
ChemicalName:5,6-Dimethyl-9-oxo-9H-xanthene-4-aceticacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

mSTINGagonist;selectiveformouseSTINGoverhumanSTING.InducesIFN-βandcytokineproductionfrombonemarrow-deriveddendriticcells.Causestumorregressionfollowingintratumoraladministrationinmousetumormodels.Inducesanadaptiveimmuneresponsetoreducesystemictumorgrowthandprovidesimmunologicalmemoryagainstautologoustumorre-challenge.Alsoantiviral.

TechnicalData

M.Wt282.29
FormulaC17H14O4
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber117570-53-3
PubChemID123964
InChIKeyXGOYIMQSIKSOBS-UHFFFAOYSA-N
SmilesO=C1C2=CC=CC(CC(O)=O)=C2OC3=C1C=CC(C)=C3C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO5.6520
ethanol1.415mMwithsonication

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight282.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.54mL17.71mL35.42mL
5mM0.71mL3.54mL7.08mL
10mM0.35mL1.77mL3.54mL
50mM0.07mL0.35mL0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet