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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/DMF/4512/50/50 mg
产品编号:4512/50
市  场 价:¥980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$49.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/DMF/4512/50/50 mg
商品介绍
Description:Nrf2pathwayactivator;neuroprotective
AlternativeNames:Dimethylfumarate
ChemicalName:2(E)-Butenedioicacid1,4-dimethylester
Purity:≥99%
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Nuclearfactor(erythroid-derived)-like2(Nrf2)pathwayactivator;inducesupregulationofantioxidantgeneexpression.Displayscytoprotectiveeffectsinhumanspinalcordastrocytes,oligodendrocyteprecursorcellsandhippocampalneuronsfollowinghydrogenperoxidechallenge.Exertsneuroprotectiveeffectsinvivoinexperimentalautoimmuneencephalomyelitis.Primarymetabolite(MMF,Cat.No.4511)available.

TechnicalData

M.Wt144.13
FormulaC6H8O4
StorageStoreatRT
Purity≥99%
CASNumber624-49-7
PubChemID637568
InChIKeyLDCRTTXIJACKKU-ONEGZZNKSA-N
SmilesO=C(/C=C/C(OC)=O)OC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO14.41100
ethanol7.2150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight144.13.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM6.94mL34.69mL69.38mL
5mM1.39mL6.94mL13.88mL
10mM0.69mL3.47mL6.94mL
50mM0.14mL0.69mL1.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet