SelectiveagonistoftheorphannuclearreceptorLRH-1(liverreceptorhomolog-1,NR5A2)invitro.Inducesbileacidbiosyntheticenzymes;increasesbileacidanddecreaseshepatictriglyceridesandserumglucose.Exhibitsantidiabeticeffects.
| M.Wt | 621.83 |
| Formula | C32H64NO8P |
| Storage | Storeat-20°C |
| CASNumber | 18194-25-7 |
| PubChemID | 512874 |
| InChIKey | IJFVSSZAOYLHEE-SSEXGKCCSA-N |
| Smiles | [O-]P(OC[C@H](OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)(OCC[N+](C)(C)C)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| ethanol | 62.18 | 100 |
Thefollowingdataisbasedontheproductmolecularweight621.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.61mL | 8.04mL | 16.08mL |
| 5mM | 0.32mL | 1.61mL | 3.22mL |
| 10mM | 0.16mL | 0.8mL | 1.61mL |
| 50mM | 0.03mL | 0.16mL | 0.32mL |



