Selectiveagonistofhydroxycarboxylicacidreceptor1(HCA1,alsoknownasGPR81)(EC50~150μM).Inhibitslipolysisinwild-typemouseADIpocytes.DisplaysminimalactivityatHCA2(atconcentrations>10mM)andnoactivityatHCA3,freefattyacidreceptor(FFAR)2orFFAR3.
M.Wt | 154.12 |
Formula | C7H6O4 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 99-10-5 |
PubChemID | 7424 |
InChIKey | UYEMGAFJOZZIFP-UHFFFAOYSA-N |
Smiles | OC1=CC(O)=CC(C(O)=O)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 15.41 | 100 | |
ethanol | 15.41 | 100 | |
water | 15.41 | 100 |
Thefollowingdataisbasedontheproductmolecularweight154.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 6.49mL | 32.44mL | 64.88mL |
5mM | 1.3mL | 6.49mL | 12.98mL |
10mM | 0.65mL | 3.24mL | 6.49mL |
50mM | 0.13mL | 0.65mL | 1.3mL |