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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/2,3-DCPE hydrochloride/2137/50/50 mg
产品编号:2137/50
市  场 价:¥7500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$375.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/2,3-DCPE hydrochloride/2137/50/50 mg
商品介绍
Description:Selectivelyinducescancercellapoptosis
ChemicalName:2-[[3-(2,3-Dichlorophenoxy)propyl]amino]ethanolhydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivelyinducesapoptosisanddownregulatesBcl-XLproteinexpressioninvarioushumancancercellsversusnormalcellsinvitro.IC50valuesare0.89and12.6μMforLoVohumancoloncancercelllineandnormalhumanfibroblastsrespectively.Inducesp21expressionandS-phasearrestincancercellsviaERK-mediatedpathways.

TechnicalData

M.Wt300.61
FormulaC11H15Cl2NO2.HCl
StorageDesiccateat-20°C
Purity≥99%(HPLC)
CASNumber1009555-55-8
PubChemID52913859
InChIKeyGFCJFYSIPRIHKT-UHFFFAOYSA-N
SmilesCl.OCCNCCCOC1=C(Cl)C(Cl)=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
phosphatebufferedsaline30.06100
water30.06100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight300.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.33mL16.63mL33.27mL
5mM0.67mL3.33mL6.65mL
10mM0.33mL1.66mL3.33mL
50mM0.07mL0.33mL0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet