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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Cyclosporin A/1101/100/100 mg
产品编号:1101/100
市  场 价:¥2300.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$115.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Cyclosporin A/1101/100/100 mg
商品介绍
Description:Calcineurininhibitor
AlternativeNames:CiclosporinA
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Immunosuppressant;inhibitsphosphataseactivityofcalcineurin(IC50=5nM).AlsoinhibitsformationandopeningofthemitochondrialpermeABIlitytransitionpore(MPTP).

CompoundLibraries

CyclosporinAisalsoofferedaspartoftheTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt1202.63
FormulaC62H111N11O12
StorageDesiccateat-20°C
Purity≥99%(HPLC)
CASNumber59865-13-3
PubChemID2909
InChIKeyPMATZTZNYRCHOR-UHFFFAOYSA-N
SmilesOC(C(CC=CC)C)C1C(=O)NC(C(=O)N(C)CC(N(C)C(CC(C)C)C(NC(C(=O)N(C)C(CC(C)C)C(NC(C)C(=O)NC(C)C(N(C)C(C(N(C)C(C(N(C)C(C(C)C)C(=O)N1C)=O)CC(C)C)=O)CC(C)C)=O)=O)C(C)C)=O)=O)CC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO120.26100
ethanol60.1350

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1202.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.83mL4.16mL8.32mL
5mM0.17mL0.83mL1.66mL
10mM0.08mL0.42mL0.83mL
50mM0.02mL0.08mL0.17mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet