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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Cyclophosphamide/4091/50/50 mg
产品编号:4091/50
市  场 价:¥1180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$59.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Cyclophosphamide/4091/50/50 mg
商品介绍
Description:Alkylatingagent;chemotherapeutic
ChemicalName:2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine2-oxide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Nitrogenmustardalkylatingagentandprodrug.Phosphoramidemustard(activemetabolite)formsDNAcross-linksleADIngtocelldeath.Inhibitsaldehydedehydrogenase1(ALDH1)throughitsdegradationproductacrolein.Chemotherapeuticforthetreatmentofbreastcancer;regulatesBaxandBcl-2expressionwhenadmiNISTeredwithetoposide(Cat.No.1226)inbreastcancercelllines.

TechnicalData

M.Wt261.09
FormulaC7H15Cl2N2O2P
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber50-18-0
PubChemID2907
InChIKeyCMSMOCZEIVJLDB-UHFFFAOYSA-N
SmilesO=P1(N(CCCl)CCCl)OCCCN1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.11100
water26.11100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight261.09.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.83mL19.15mL38.3mL
5mM0.77mL3.83mL7.66mL
10mM0.38mL1.92mL3.83mL
50mM0.08mL0.38mL0.77mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet