Inhibitorofhedgehog(Hh)signaling,likelyviadirectinhibitionofSmoothened,theaccessoryproteintotheputativeHhreceptorPatched.Anticancerandteratogenicinvivo.Depletesstem-likecancercellsinglioblastomaandblockstumorengraftment.Canalsobeusedtoinducedifferentiationofhumanembryonicstemcells(hESCs)intohormone-expressingendocrinecells.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight411.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.