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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Clotrimazole/4096/50/50 mg
产品编号:4096/50
市  场 价:¥1180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$59.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Clotrimazole/4096/50/50 mg
商品介绍
Description:CytochromeP450inhibitor;antifungal
AlternativeNames:CLT
ChemicalName:1-(2-Chloro-α,α-diphenylbenzyl)imidazole
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ImidazoleantimycoticandcytochromeP450inhibitor.InhibitsCa2+-activatedK+current(IC50=3μM)andL-typeCa2+current;increasesthefiringrateofactionpotentials.Exhibitsantiproliferativeactivityinvitroandinvivo.AlsoaninverseagoNISTofthehumanconstitutiveandrostanereceptor(hCAR).

CompoundLibraries

ClotrimazoleisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt344.84
FormulaC22H17ClN2
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber23593-75-1
PubChemID2812
InChIKeyVNFPBHJOKIVQEB-UHFFFAOYSA-N
SmilesClC1=CC=CC=C1C(C3=CC=CC=C3)(C4=CC=CC=C4)N2C=CN=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO25.8675
ethanol34.48100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight344.84.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.9mL14.5mL29mL
5mM0.58mL2.9mL5.8mL
10mM0.29mL1.45mL2.9mL
50mM0.06mL0.29mL0.58mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet