Potentsteroidalandrogenreceptoragonist(IC50=12nM).Mimicstheactionof5α-dihydrotestosterone(DHT).Transactivatesthemousemammarytumorvirus(MMTV)promoter;repressesMMP1promoteractivity.Inhibits5α-reductasetypeIandII(IC50valuesare6and10nMrespectively).
M.Wt | 441.01 |
Formula | C26H33ClN2O2 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 188589-66-4 |
PubChemID | 90488881 |
InChIKey | CTVXDPDUOKQBKZ-BLIBDJTASA-N |
Smiles | O=[C@](NC5=CC=CC=C5Cl)[C@H]4CC[C@@]3([H])[C@]2([H])CCC1N(C)C(C=C[C@@](C)1[C@]([H])2CC[C@]34C)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 4.41 | 10 | |
ethanol | 4.41 | 10 |
Thefollowingdataisbasedontheproductmolecularweight441.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.27mL | 11.34mL | 22.68mL |
5mM | 0.45mL | 2.27mL | 4.54mL |
10mM | 0.23mL | 1.13mL | 2.27mL |
50mM | 0.05mL | 0.23mL | 0.45mL |