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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Cl-4AS-1/3812/10/10 mg
产品编号:3812/10
市  场 价:¥4180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$209.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Cl-4AS-1/3812/10/10 mg
商品介绍
Description:SteroidalandrogenreceptoragoNIST
ChemicalName:(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)-N-(2-Chlorophenyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4,6a-trimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentsteroidalandrogenreceptoragonist(IC50=12nM).Mimicstheactionof5α-dihydrotestosterone(DHT).Transactivatesthemousemammarytumorvirus(MMTV)promoter;repressesMMP1promoteractivity.Inhibits5α-reductasetypeIandII(IC50valuesare6and10nMrespectively).

TechnicalData

M.Wt441.01
FormulaC26H33ClN2O2
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber188589-66-4
PubChemID90488881
InChIKeyCTVXDPDUOKQBKZ-BLIBDJTASA-N
SmilesO=[C@](NC5=CC=CC=C5Cl)[C@H]4CC[C@@]3([H])[C@]2([H])CCC1N(C)C(C=C[C@@](C)1[C@]([H])2CC[C@]34C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.4110
ethanol4.4110

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight441.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.27mL11.34mL22.68mL
5mM0.45mL2.27mL4.54mL
10mM0.23mL1.13mL2.27mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet