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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Cardamonin/2509/10/10 mg
产品编号:2509/10
市  场 价:¥3180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$159.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Cardamonin/2509/10/10 mg
商品介绍
Description:InhibitorofNF-κBactivation;anti-inflammatory
ChemicalName:(2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Chaloneanalogthatdisplayanti-inflammatoryactivity.InhibitsNOandPGE2productionfromLPS-andIFN-γ-inducedRAWcellsandinhibitsTXB2productionviatheCOX-1andCOX-2pathways.InhibitsNF-κBactivationviainhibitionofIκBαdegradationandphosphorylation,IκBkinaseactivationandNF-κBnucleartranslocation.

TechnicalData

M.Wt270.28
FormulaC16H14O4
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber19309-14-9
PubChemID641785
InChIKeyNYSZJNUIVUBQMM-BQYQJAHWSA-N
SmilesOC1=CC(O)=C(C(/C=C/C2=CC=CC=C2)=O)C(OC)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO27.03100
ethanol5.4120

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight270.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.7mL18.5mL37mL
5mM0.74mL3.7mL7.4mL
10mM0.37mL1.85mL3.7mL
50mM0.07mL0.37mL0.74mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet