Antitumoragentthatformsplatinum-DNAadducts.Causesintra-andinterstrandDNAcrosslinksblockingDNAreplicationandtranscription.EnhancesrADIation-inducedsingle-strandDNAbreakageanddisplayslowernephrotoxicitythananalogcisplatin(Cat.No.2251).
M.Wt | 371.25 |
Formula | C6H12N2O4Pt |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 41575-94-4 |
PubChemID | 10339178 |
InChIKey | OLESAACUTLOWQZ-UHFFFAOYSA-L |
Smiles | O=C(C21CCC2)O[Pt-2]([NH3+])([NH3+])OC1=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
water | 9.28 | 25 |
Thefollowingdataisbasedontheproductmolecularweight371.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.69mL | 13.47mL | 26.94mL |
5mM | 0.54mL | 2.69mL | 5.39mL |
10mM | 0.27mL | 1.35mL | 2.69mL |
50mM | 0.05mL | 0.27mL | 0.54mL |