Prototypicvanilloidreceptoragonist(pEC50valuesare7.97and7.10atratandhumanVR1receptorsrespectively).Excitesasubsetofprimaryafferentsensoryneurons,withsubsequentantinociceptiveandanti-inflammatoryeffects.ReversIBLyinhibitsaggregationofplatelets.AlsoavailableaspartoftheVanilloidTRPV1ReceptorTocriset™.
| M.Wt | 305.42 |
| Formula | C18H27NO3 |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 404-86-4 |
| PubChemID | 1548943 |
| InChIKey | YKPUWZUDDOIDPM-SOFGYWHQSA-N |
| Smiles | COC1=C(O)C=CC(CNC(=O)CCCCC=CC(C)C)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 15.27 | 50 | |
| ethanol | 15.27 | 50 |
Thefollowingdataisbasedontheproductmolecularweight305.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.27mL | 16.37mL | 32.74mL |
| 5mM | 0.65mL | 3.27mL | 6.55mL |
| 10mM | 0.33mL | 1.64mL | 3.27mL |
| 50mM | 0.07mL | 0.33mL | 0.65mL |



