ActivemetaboliteofvitaminD3thatactivatesthevitaminDreceptor(VDR).Displayscalcemicactions;stimulatesintestinalandrenalCa2+absorptionandregulatesboneCa2+turnover.Exhibitsantitumoractivity;inhibitsinvivoandinvitrocellproliferationinawiderangeofcellsincludingbreast,prostate,colon,skinandbraincarcinomasandmyeloidleukemiacells.
M.Wt | 416.64 |
Formula | C27H44O3 |
Storage | Desiccateat-20°C |
Purity | ≥99%(HPLC) |
CASNumber | 32222-06-3 |
PubChemID | 5280453 |
InChIKey | GMRQFYUYWCNGIN-NKMMMXOESA-N |
Smiles | C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](CCCC(C)(C)O)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)C1=C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solubility | SolubleinDMSOandinethanol |
Thefollowingdataisbasedontheproductmolecularweight416.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.4mL | 12mL | 24mL |
5mM | 0.48mL | 2.4mL | 4.8mL |
10mM | 0.24mL | 1.2mL | 2.4mL |
50mM | 0.05mL | 0.24mL | 0.48mL |