VitaminD3analogthatdisplaysminimaleffectsoncalciumhomeostasis.Regulatescelldifferentiationandproliferation;exhibitsantiproliferativeactivityagainsthumanHL-60,HL60/MX2,MCF-7,T47D,SCC-25andmouseWEHI-3cancercelllines.
| M.Wt | 412.6 |
| Formula | C27H40O3 |
| Storage | Desiccateat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 112965-21-6 |
| PubChemID | 5288783 |
| InChIKey | LWQQLNNNIPYSNX-UROSTWAQSA-N |
| Smiles | [H][C@@]12[C@]([C@]([C@@H](/C=C/[C@@H](O)C4CC4)C)([H])CC2)(C)CCC/C1=CC=C3/C([C@@H](O)C[C@H](O)C3)=C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 41.26 | 100 | |
| ethanol | 41.26 | 100 |
Thefollowingdataisbasedontheproductmolecularweight412.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.42mL | 12.12mL | 24.24mL |
| 5mM | 0.48mL | 2.42mL | 4.85mL |
| 10mM | 0.24mL | 1.21mL | 2.42mL |
| 50mM | 0.05mL | 0.24mL | 0.48mL |



