VitaminD3analogthatdisplaysminimaleffectsoncalciumhomeostasis.Regulatescelldifferentiationandproliferation;exhibitsantiproliferativeactivityagainsthumanHL-60,HL60/MX2,MCF-7,T47D,SCC-25andmouseWEHI-3cancercelllines.
M.Wt | 412.6 |
Formula | C27H40O3 |
Storage | Desiccateat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 112965-21-6 |
PubChemID | 5288783 |
InChIKey | LWQQLNNNIPYSNX-UROSTWAQSA-N |
Smiles | [H][C@@]12[C@]([C@]([C@@H](/C=C/[C@@H](O)C4CC4)C)([H])CC2)(C)CCC/C1=CC=C3/C([C@@H](O)C[C@H](O)C3)=C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 41.26 | 100 | |
ethanol | 41.26 | 100 |
Thefollowingdataisbasedontheproductmolecularweight412.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.42mL | 12.12mL | 24.24mL |
5mM | 0.48mL | 2.42mL | 4.85mL |
10mM | 0.24mL | 1.21mL | 2.42mL |
50mM | 0.05mL | 0.24mL | 0.48mL |