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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CaCCinh-A01/4877/50/50 mg
产品编号:4877/50
市  场 价:¥11700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$585.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CaCCinh-A01/4877/50/50 mg
商品介绍
Description:Calcium-activatedchloridechannel(CaCC)inhibitor
ChemicalName:6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Calcium-activatedchloridechannel(CaCC)inhibitor(IC50~10μM).InhibitsCaCCcurrentsinhumanbronchialandintestinalcells.AlsoinhibitsTMEM16Achannels(IC50=2.1μM,inTMEM16A-expressingFRTcells).

CompoundLibraries

CaCCinh-A01isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt347.43
FormulaC18H21NO4S
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber407587-33-1
PubChemID2898877
InChIKeyACLUEOBQFRYTQS-UHFFFAOYSA-N
SmilesCC(C)(C)C1CCC2=C(SC(NC(C3=CC=CO3)=O)=C2C(O)=O)C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.74100
ethanol3.4710mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight347.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.88mL14.39mL28.78mL
5mM0.58mL2.88mL5.76mL
10mM0.29mL1.44mL2.88mL
50mM0.06mL0.29mL0.58mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet