请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CYM 5541/4897/50/50 mg
产品编号:4897/50
市  场 价:¥13700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$685.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CYM 5541/4897/50/50 mg
商品介绍
Description:SelectiveS1P3receptorallostericagoNIST
ChemicalName:N,N-Dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivesphingosine-1-phosphatereceptor3(S1P3)allostericagonist(EC50=72-132nM).OccupiesadifferentspacewithintheligandbindingpocketofS1P3thanS1P.DisplaysnoactivityatS1P1,S1P2,S1P4andS1P5receptorsatconcentrationsupto10μM.Showsnosignificantactivitiesinaprofilingpanelof55GPCRs,ionchannelsandtransporters.

CompoundLibraries

CYM5541isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt316.44
FormulaC19H28N2O2
StorageStoreat+4°C
Purity≥97%(HPLC)
CASNumber945128-26-7
PubChemID17253208
InChIKeyNDKGACIWVAOUQH-UHFFFAOYSA-N
SmilesO=C(N(C3CCCCC3)C2CCCCC2)C1=NOC(C4CC4)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO31.64100
ethanol15.8250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight316.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.16mL15.8mL31.6mL
5mM0.63mL3.16mL6.32mL
10mM0.32mL1.58mL3.16mL
50mM0.06mL0.32mL0.63mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet