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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CU-T12-9/5414/10/10 mg
产品编号:5414/10
市  场 价:¥3700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CU-T12-9/5414/10/10 mg
商品介绍
Description:PotentTLR1/2agoNIST
ChemicalName:N-Methyl-4-nitro-2-(4-(4-trifluoromethyl)phenyl)-1H-imidazol-1-yl)aniline
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentTLR1/2agonist(EC50=52.9nM).ActivatestheNF-κBpathwayandupregulatesproinflammatorycytokinesinvitro.AlsoenhancesTLR1andTLR2dimerization.

LicensingInformation

SoldunderlicensefromtheUniversityofColorado

CompoundLibraries

CU-T12-9isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt362.31
FormulaC17H13F3N4O2
StorageStoreat+4°C
Purity≥99%(HPLC)
PubChemID91826088
InChIKeyLITXVDAFEYLWQE-UHFFFAOYSA-N
SmilesCNC1=CC=C([N+]([O-])=O)C=C1N2C=C(C3=CC=C(C(F)(F)F)C=C3)N=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO36.23100
ethanol7.2520

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight362.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.76mL13.8mL27.6mL
5mM0.55mL2.76mL5.52mL
10mM0.28mL1.38mL2.76mL
50mM0.06mL0.28mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet