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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CPT 11/2688/10/10 mg
产品编号:2688/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CPT 11/2688/10/10 mg
商品介绍
Description:DNAtopoisomeraseIinhibitor;antitumor
AlternativeNames:Irinotecan,Camptothecin11
ChemicalName:(4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylicacidesterhydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofDNAtopoisomeraseIthatdisplaysantitumoractivityagainstarangeoftumortypes.Activemetaboliteavailable(SN38,Cat.No.2684).

CompoundLibraries

CPT11isalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt623.14
FormulaC33H38N4O6.HCl
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber100286-90-6
PubChemID74990
InChIKeyGURKHSYORGJETM-WAQYZQTGSA-N
SmilesCCC2=C4C(C(N3C4)=CC([C@](CC)(O)C(OC5)=O)=C5C3=O)=NC1=CC=C(OC(N6CCC(N7CCCCC7)CC6)=O)C=C12.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO62.31100
water3.125mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight623.14.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.6mL8.02mL16.05mL
5mM0.32mL1.6mL3.21mL
10mM0.16mL0.8mL1.6mL
50mM0.03mL0.16mL0.32mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet