Potent,non-peptideKV1.3channelantagoNISTthatpreferentiallybindstotheC-typeinactivatedstateofthechannel(IC50~200nM).InhibitsKV1.4withanIC50of~300nM.SelectiveoverKV1.1,KV1.2,KV1.5,KV1.6,KV3.1-4,andKV4.2.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight340.89.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.