Carbonmonoxide-releasingmolecule.Causesvasodilatationinisolatedaorticringsinvitro.Cytotoxictosmoothmusclecellsinvitroafterprolonged(24h)exposure.Exhibitsantihypertensiveeffectsinvivo.Reducestight-junctiondisruptioninintestinalmucosainaratsepsismodel.
M.Wt | 512.01 |
Formula | C6Cl4O6Ru2 |
Storage | StoreatRT |
CASNumber | 22594-69-0 |
PubChemID | 10951331 |
InChIKey | JYHHJVKGDCZCCL-UHFFFAOYSA-J |
Smiles | [Cl-][Ru++]1([Cl-][Ru++]([Cl-])([Cl-]1)(C#[O])(C#[O])C#[O])(C#[O])(C#[O])C#[O] |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 51.2 | 100 |
Thefollowingdataisbasedontheproductmolecularweight512.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.95mL | 9.77mL | 19.53mL |
5mM | 0.39mL | 1.95mL | 3.91mL |
10mM | 0.2mL | 0.98mL | 1.95mL |
50mM | 0.04mL | 0.2mL | 0.39mL |