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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CMPD101/5642/10/10 mg
产品编号:5642/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>白蛋白>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CMPD101/5642/10/10 mg
商品介绍
Description:PotentandselectiveGRK2/3inhibitor
ChemicalName:3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveGRK2/3inhibitor(IC50valuesare32and54nMforGRK3andGRK2,respectively).ExhibitsselectivityforGRK2/3overGRK1/5.ReducesDAMGO-induceddesensitizationandinternalizationofμ-opioidreceptors.

TechnicalData

M.Wt466.46
FormulaC24H21F3N6O
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber865608-11-3
PubChemID11677079
InChIKeyWFOVEDJTASPCIR-UHFFFAOYSA-N
SmilesCN1C(CNC2=CC(C(NCC3=CC=CC=C3C(F)(F)F)=O)=CC=C2)=NN=C1C4=CC=NC=C4

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO46.65100
ethanol46.65100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight466.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.14mL10.72mL21.44mL
5mM0.43mL2.14mL4.29mL
10mM0.21mL1.07mL2.14mL
50mM0.04mL0.21mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet