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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CKD 602/5125/10/10 mg
产品编号:5125/10
市  场 价:¥1180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$59.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CKD 602/5125/10/10 mg
商品介绍
Description:TopoisomeraseIinhibitor
AlternativeNames:Belotecan,Camtobell®
ChemicalName:(4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dionephosphate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

TopoisomeraseIinhibitor.FormsstableDNA-topoisomerasecomplexesduringDNAreplicationandinducescellcyclearrestintheG2/Mphase.Inhibitsgrowthofarangeofcancercelllinesinvitro,aswellasofovarianandleukemiatumorsinvivo.

TechnicalData

M.Wt531.49
FormulaC25H27N3O4.HCl
StorageStoreat-20°C
Purity≥98%(HPLC)
PubChemID123773277
InChIKeyNWUOSUHZEZPOPE-UQIIZPHYSA-N
SmilesO=C1C2=C([C@](CC)(O)C(OC2)=O)C=C3C4=NC5=CC=CC=C5C(CCNC(C)C)=C4CN31.OP(O)(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO53.15100
water10.6320

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight531.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.88mL9.41mL18.82mL
5mM0.38mL1.88mL3.76mL
10mM0.19mL0.94mL1.88mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet