Inhibitorofhumanandbovineactin-relatedprotein2/3(Arp2/3)complex.Inhibitsactinpolymerization(IC50=11μM).DoesnotinhibitbuddingorfissionyeastArp2/3complexes.
M.Wt | 394.28 |
Formula | C17H16BrNO3S |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 388592-44-7 |
PubChemID | 3574452 |
InChIKey | MVWNPZYLNLATCH-UHFFFAOYSA-N |
Smiles | O=C1N(C3=CC=C(OC)C=C3OC)C(C2=CC=CC(Br)=C2)SC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 39.43 | 100 | |
ethanol | 3.94 | 10mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight394.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.54mL | 12.68mL | 25.36mL |
5mM | 0.51mL | 2.54mL | 5.07mL |
10mM | 0.25mL | 1.27mL | 2.54mL |
50mM | 0.05mL | 0.25mL | 0.51mL |