PotentCARantagonist(IC50=70nM).Exhibits>90-foldselectivityforCARoverpregnaneXreceptor(PXR).AlsoselectiveoverapanelofothernuclearreceptorsincludingFXR,LXR,PPARγandRXR.
CINPA1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 395.49 |
Formula | C23H29N3O3 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 102636-74-8 |
PubChemID | 969470 |
InChIKey | AYQBYSPEGRYKFA-UHFFFAOYSA-N |
Smiles | O=C(CN(CC)CC)N1C2=C(C=CC=C2)CCC3=C1C=C(NC(OCC)=O)C=C3 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 39.55 | 100 | |
ethanol | 39.55 | 100 |
Thefollowingdataisbasedontheproductmolecularweight395.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.53mL | 12.64mL | 25.29mL |
5mM | 0.51mL | 2.53mL | 5.06mL |
10mM | 0.25mL | 1.26mL | 2.53mL |
50mM | 0.05mL | 0.25mL | 0.51mL |