SelectiveTRPM3agonist.ExhibitsselectivityforTRPM3overTRPM1,TRPM2andTRPM4-8.Stimulatesinsulinreleasefrompancreaticisletcellsinvitro.Evokesnocifensivebehaviorinmice.
CIM0216isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 347.41 |
| Formula | C21H21N3O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1031496-06-6 |
| PubChemID | 42887770 |
| InChIKey | KSEXDSJYVSEVGF-UHFFFAOYSA-N |
| Smiles | O=C(NC1=NOC(C)=C1)C(C2=CC=CC=C2)N(CCC3)C4=C3C=CC=C4 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.74 | 100 | |
| ethanol | 17.37 | 50 |
Thefollowingdataisbasedontheproductmolecularweight347.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.88mL | 14.39mL | 28.78mL |
| 5mM | 0.58mL | 2.88mL | 5.76mL |
| 10mM | 0.29mL | 1.44mL | 2.88mL |
| 50mM | 0.06mL | 0.29mL | 0.58mL |



