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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CGP 7930/1513/10/10 mg
产品编号:1513/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CGP 7930/1513/10/10 mg
商品介绍
Description:PositivemodulatoratGABABreceptors
ChemicalName:3,5-bis(1,1-Dimethylethyl)-4-hydroxy-β,β-dimethyl-benzenepropanol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PositiveallostericmodulatorofGABABreceptors.IncreasesthepotencyandefficacyofGABAatbothnativeandrecombinantGABABreceptors(EC50valuesare5.37and4.60μMrespectively)andenhancestheinhibitoryeffectoftheagoNISTL-baclofeninculturedcorticalneurons.Reducesoperantself-administrationofethanolinalcohol-preferringratsfollowingi.p.administration.

CompoundLibraries

CGP7930isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt292.46
FormulaC19H32O2
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber57717-80-3
PubChemID5024764
InChIKeyXLWJPQQFJNGUPA-UHFFFAOYSA-N
SmilesCC(C)(CO)CC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO29.25100
ethanol29.25100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight292.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.42mL17.1mL34.19mL
5mM0.68mL3.42mL6.84mL
10mM0.34mL1.71mL3.42mL
50mM0.07mL0.34mL0.68mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet