PotentandselectiveinhibitorofregulatorofG-proteinsignaling4(RGS4)protein(IC50valuesare30.1nMand11.0μMforRGS4andRGS8respectively).Exhibits>20-foldselectivityforRGS4overotherRGSproteins.
CCG50014isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 316.35 |
Formula | C16H13FN2O2S |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 883050-24-6 |
PubChemID | 2733079 |
InChIKey | QUIIIYITNGOFEI-UHFFFAOYSA-N |
Smiles | FC(C=C3)=CC=C3CN(C(N(C2=CC=C(C)C=C2)S1)=O)C1=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 31.64 | 100 |
Thefollowingdataisbasedontheproductmolecularweight316.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.16mL | 15.81mL | 31.61mL |
5mM | 0.63mL | 3.16mL | 6.32mL |
10mM | 0.32mL | 1.58mL | 3.16mL |
50mM | 0.06mL | 0.32mL | 0.63mL |