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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CC 0651/4503/10/10 mg
产品编号:4503/10
市  场 价:¥5500.00
场      地:美国(厂家直采)
产品分类: 分子类>核酸酶类>连接酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$275.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CC 0651/4503/10/10 mg
商品介绍
Description:AllostericinhibitorofhCdc34
ChemicalName:(2R,3S,4S)-5-[4-(3,5-Dichlorophenyl)phenyl]-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AllostericinhibitorofhumanCdc34.InhibitshCdc34-mediatedubiquitinationofp27Kip1(IC50=1.72μM).ExhibitsselectivityforhCdc34overUba1,Ube2G1,UbcH7,UbcH5,Ube2N(Ubc13),Ube2R2,SMURF2,SspH1andRnf168.

TechnicalData

M.Wt442.29
FormulaC20H21Cl2NO6
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1319207-44-7
PubChemID53239927
InChIKeyNTCBTNCWNRCBGX-YTQUADARSA-N
SmilesClC1=CC(Cl)=CC(C2=CC=C(C[C@H](NC(COC)=O)[C@@H]([C@H](C(O)=O)O)O)C=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.NaOH44.23100
DMSO44.23100
ethanol22.1150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight442.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.26mL11.3mL22.61mL
5mM0.45mL2.26mL4.52mL
10mM0.23mL1.13mL2.26mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet