请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CALP1/2090/1/1 mg
产品编号:2090/1
市  场 价:¥2980.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CALP1/2090/1/1 mg
商品介绍
Description:Cell-permeablecalmodulinagoNIST
AlternativeNames:Calcium-likepeptide1
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cell-permeablecalmodulin(CaM)agonistthatbindstotheEF-hand/Ca2+-bindingsite;producesCaM-dependentactivationofphosphodiesterase.AlsobindstocytoplasmicsitesonotherCa2+channels,includingNMDA andHIV-1gp120-activatedchannels,inhibitingCa2+-mediatedcytotoxicityandapoptosis(IC50=52μM).Showntoprotectpancreaticacinarcellsfromgossypol(Cat.No.1964)inducednecrosis.InhibitsVLA-5-mediatedadhesionofmastcellstofibronectininvitroandattenuatesinflammatorycellinfluxinguineapiglunginvivo.

TechnicalData

M.Wt842.09
FormulaC40H75N9O10
SequenceVAITVLVK
StorageDesiccateat-20°C
CASNumber145224-99-3
PubChemID10440555
InChIKeyHTOHLCKNMRKYLK-KVZSNLRASA-N
Smiles[H]N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight842.09.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.19mL5.94mL11.88mL
5mM0.24mL1.19mL2.38mL
10mM0.12mL0.59mL1.19mL
50mM0.02mL0.12mL0.24mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet